Curriculim Vitae

Education and Training

9/76-6/79

Bachelor of Science Texas A & M University

B.S. Degree

College Station, Texas

Postgraduate

7/79-6/83

Baylor College of Medicine, Houston, Texas

M.D. Degree

7/83-6/84

Intern in Obstetrics and Gynecology

Baylor College of Medicine, Houston, Texas

7/84-6/87

Resident in Obstetrics and Gynecology

Baylor College of Medicine, Houston, Texas

7/86-6/87

Chief Resident in Obstetrics and Gynecology

Baylor College of Medicine, Houston, Texas

7/87-6/88

Medical Endocrinology Fellow

Baylor College of Medicine, Houston, Texas

7/88-6/90

Reproductive Endocrinology and Infertility Fellow

Baylor College of Medicine, Houston, Texas

Appointments and Positions

Baylor College of Medicine

Clinical Assistant Professor, Department of Obstetrics and Gynecology

Certification and Licensure

Texas Medical License G5720, 6/83 by FLEX examination

Board Certification in Obstetrics and Gynecology, 1992. Recertified 2001

Board Certification in Reproductive Endocrinology, 1994. Recertified 2001.

Memberships in Professional and Scientific Societies

• Accreditation Council for Gynecologic Endoscopy, Inc.
• American College of Obstetrics and Gynecology
• American Society for Reproductive Medicine (ASRM)
• American Medical Association
• Harris County Medical Society
• Hispanic-American Medical Association of Houston
• Houston Gynecological and Obstetrical Society
• Society of Reproductive Endocrinologists
• Society of Reproductive Surgeons
• Texas Medical Foundation

Honors and Awards

• B.S. degree with honors, Summa Cum Laude
• Phi Kappa Phi Honor Society, 1979
• Undergraduate Fellow Program, Texas A&M, 1979 - "Diagnosis of Dirofilaria Immitis in Dogs"
• Mead Johnson ACOG Junior Fellow Award, 1986
• ACOG-Ortho Distinguished Fellowship Award 1989-1990
• Prize Paper Society of Reproductive Endocrinology, Annual Meeting of the American Fertility Society, October 1990.
• Volunteer Faculty of the Year Award, 1992-1993, Department of Obstetrics and Gynecology - Baylor College of Medicine
• Best Doctors - Best Doctors, Inc., 2002-2006
• Super Doctors - Key Professional Media, Inc., 2004-2006
• Top Doctors - H Texas Magazine, 2005-2006
• Cambridge Who's Who Among Women Specialty Physicians in Healthcare, 2006-2007

Professional Activities

Baylor College of Medicine

Admissions Committee Student Representative, 1979-1980

ACOG District VII, Texas Section, Junior Fellow

Vice-Chairman 1985-1986, Chairman 1986-1987

Faculty American Fertility Society Laser Course

Houston Laser Institute, Texas Woman's Hospital Houston Texas 1987-1990.

ACOG-Ortho Distinguished Fellow Award 1989-1990

Member of the Infertility Network Medical Advisory Board 1996 - 1998

SREI Nominating Committee

The Society of Reproductive Endocrinology and Infertility, Inc. 1998-1999

ASRM CPT/RBRVS Coding Committee

American Society for Reproductive Medicine 1996-1998

Director - Obstetrical and Gynecological Associates, P.A., Board of Directors 1996-1998

ASRM October, 2004 annual meeting moderator for scientific sessions Philadelphia Pa.

ASRM Prize Poster Judge for Scientific Sessions 2005

Examiner American Board of Obstetrics and Gynecology Reproductive Endocrinology and Infertility 2000-present

Invitational Lectures

IV Encuentro Internacional de Ginecologia y Obstetricia

Monterrey, N.L. Mexico

September 1990

Hyperandrogenism and Insulin Resistance

Hyperprolactinemia

2nd Central American Regional Meeting of SLASOG

Central American Congress of Gynecology and Obstetrics

San Jose, Costa Rica

November 26, 27, 1989

District VII Meeting, Junior Fellowship Representative

American College of Obstetricians and Gynecologists

Panama City, Panama

1986

Research Grant Awards

• The effect of diabetes on the rat estrous cycle. 1987-1988; Biomedical Research Support Grant USPHS Grant No. RR-05425
• Short term danazol versus lupron for pelvic endometriosis. 1987-1989. TAP Pharmaceuticals.
• Insulin resistance and hyperandrogenism. 1989-1990; ACOG-Ortho Distinguished Fellowship Grant.
• Insulin resistance and hyperandrogenic states. 1989-1990; The Women's Fund Research Grant.
• Late onset congenital adrenal hyperplasia: hormonal and DNA diagnosis in women with various gynecologic disorders. 1989-1990; The Women's Fund Research Grant.
• Serono Study 24785: A phase IIIb, prospective, multicenter trial to evaluate patient satisfaction with follitropin alfa injection applied by Pen device compared to other injectable gonadotropins in oligoanovulatory infertile women undergoing ovulation induction. 2004-2005; Serono, Inc.

Publications

Scientific Papers

1. Valdes C, Malini S, Malinak LR. Sonography in the surgical management of vaginal and cervical atresia. Fertil Steril. 40(2):263-5, 1983.
2. Valdes C, Malinak LR, Malini S. Ultrasound evaluation of female genital tract anomalies: a review of 64 cases. Am J Obstet Gynecol. 149(3):285-92, 1984.
3. Malini S, Valdes C, Malinak LR. Sonographic diagnosis and classification of anomalies of the female genital tract. J Ultrasound Med. 3(9): 397-404, 1984.
4. Greenberg F, Valdes C, Rosenblatt HM , Kirkland JL , Ledbetter DH. Hypoparathyroidism and T cell immune defect in a patient with 10p deletion syndrome. J of Pediatr. 109(3):489-92, 1986.
5. Ginsberg KA, Valdes C, Schnider G. Spontaneous utero-ovarian vessel rupture during pregnancy: three case reports and a review of the literature. Obstet Gynecol. 69(3 Pt 2):474-6, 1987.
6. Valdes CT, Elkind-Hirsch KE, Rogers DG. Diabetes-induced alterations of reproductive and adrenal function in the female rat. Neuroendocrinology. 51(4):406-12, 1990.
7. Rogers DG, Valdes CT, Elkind-Hirsch KE. The effect of ovarian function on insulin-like growth factor I plasma levels and hepatic IGF-I mRNA levels in diabetic rats treated with insulin. Diabetes Res Clin Pract. 8(3):235-42, 1990.
8. Coronado C, Franklin RR, Lotze EC, Bailey HR, Valdes CT. Surgical treatment of symptomatic colorectal endometriosis. Fertil Steril. 53(3):411-6, 1990.
9. Navarro C, Franklin RR, Valdes CT: Supernumerary ovary in association with endometriosis. Fertil Steril. 54(1):164-5, 1990.
10. Valdes CT, Elkind-Hirsch KE, Rogers DG, Adelman JP. The hypothalamic-pituitary axis of streptozotocin-induced diabetic female rats is not normalized by estradiol replacement. Endocrinology. 128(1):433-40, 1991.
11. Elkind-Hirsch KE, Valdes CT, McConnell TG, Malinak LR. Androgen response to acutely increased endogenous insulin levels in hyperandrogenic and normal cycling women. Fertil Steril. 55(3):486-91, 1991.
12. Valdes CT, Elkind-Hirsch KE. Intravenous glucose tolerance test-derived insulin sensitivity changes during the menstrual cycle, J Endocrinol Metabol 72(3):642-646, 1991.
13. Elkind-Hirsch, KE, Valdes, CT, Rogers, DG. Does estradiol treatment normalize the hypothalamic-pituitary-adrenal axis in streptozotocin-induced ovariectomized diabetic female rats? Horm Metab Res. 23(10):481-5, 1991.
14. Elkind-Hirsch KE, Valdes CT, McConnell TG, Malinak LR. Androgen responses to acutely increased endogenous insulin levels in hyperandrogenic and normal cycling women. Ob/Gyn Digest. 1:25-7, 1992.
15. Elkind-Hirsch KE, Valdes CT, Malinak LR. Insulin resistance improves in hyperandrogenic women treated with Lupron. Fertil Steril. 60(4):634-41, 1993.
16. Wright S, Valdes CT, Dunn RC, Franklin RR. Short term Lupron or danazol therapy for pelvic endometriosis. Fertil Steril. 63(3):504-7, 1995.
17. Wun WS, Wun CC, Valdes CT, Dunn RC, Grunert GM. Optimal insemination concentration for human in vitro fertilization (IVF). Chin J Physiol. 40(4):227-36, 1997.
18. Wun WS, Wun CC, Valdes CT, Dunn RC, Grunert GM. Blastocyst formation is a good indicator for attainment of assisted reproduction. Chin J Physiol. 40(4):237-42, 1997.
19. Gullet J, Grunert GM, Valdes CT, Dunn RC, Wun WS. Low blastocyst formation rates in day-2 fertilized oocytes. J Assist Reprod Genet. 15(10):594-8, 1998.
20. Wun WSA, Gullet J, Dunn RC, Valdes, CT, Grunert. The development of one pronucleus "zygotes" is abnormal. Assisted Reproduction Reviews. 9(2):65-9, 1999.

Book Chapters

1. Valdes CT, Malinak LR, Franklin RF: Developmental anomalies of the vulva and vagina. In Benign Diseases of the Vulva and Vagina G K Hall Medical Publishers 2nd edition 70 Lincoln St Boston 02111 editor R H Kaufman, 1989.
2. Valdes CT, Malinak LR: The management of chronic pelvic pain: When is surgery indicated? In Clinical Decisions in Obstetrics and Gynecology. Aspen Publishers Inc., Rockville Maryland, Editor Robert C Cefalo M.D. Ph.D., 1990.

Abstracts

1. Valdes CT, Malinak LR, Malini S. Ultrasound evaluation of female genital tract anomalies: a review of 64 cases. Central Association of OB/GYN, November 1983.
2. Valdes CT, Ginsburg K. Spontaneous uterine vein rupture: Diagnosis treatment and review of the literature. The Society of Gynecologic Surgeons Fourth Annual Meeting, March 1986.
3. Valdes CT, Malinak LR. Unilateral cystic vulvar masses presenting as hernias: Differential diagnosis and surgical management. Society of Gynecologic Surgeons Fourth Annual Meeting, March 1986.
4. Raynolds M, Elkind-Hirsch KE, Valdes CT. Comparison of hypothalamic GnRH mRNA production and GnRH concentrations in normal and streptozotocin diabetic female rats. Neurosciences Symposium, May 1988.
5. Valdes CT, Elkind-Hirsch KE, Rogers DG. Altered Hypothalamic GnRH Concentration in the Female Streptozotocin Diabetic Rat. The Endocrine Society, June 1988.
6. Rogers DG, Valdes CT, Elkind-Hirsch KE. Importance of ovarian function on insulin-like growth factor I (IGF-I) production in normal and treated diabetic rats. The American Diabetes Association, June 1988.
7. Elkind-Hirsch KE, Valdes CT. Does estradiol (E2) replacement normalize adrenal function in diabetic female rats? Society For Gynecologic Investigation, March 1989.
8. Valdes CT, Elkind-Hirsch KE. Does estradiol replacement normalize the hypothalamic-pituitary axis of streptozotocin-induced diabetic rats? The Endocrine Society, June 1988.
9. Valdes CT, Rowe T, McConnell T, Boyd AE III. Hyperprolactinemia: Natural history, interaction with pregnancy and pituitary magnetic resonance imaging. The American Fertility Society, November 1989.
10. Valdes CT, Dunn R, Franklin R. Short term lupron or danazol therapy for pelvic endometriosis. The American Fertility Society Meeting, November 1989.
11. Valdes CT, McConnell TG, Elkind-Hirsch KE. VGTT-Derived insulin sensitivity changes during the menstrual cycle. Society for Gynecologic Investigation, March 1990.
12. Elkind-Hirsch, KE, Valdes CT, Malinak LR. Androgen response to acutely increased insulin levels in normal and PCO women. Society for Gynecologic Investigation, March 1990.
13. Elkind-Hirsch, KE, Valdes CT, Malinak LR, Boyd AE. Assessment of insulin sensitivity in normal and hyperandrogenic women with the minimal model approach. Clinical Research, April, 1990.
14. Valdes CT, Elkind-Hirsch KE, Mawad M, Boyd AE III. Changes in the pituitary gland during the normal menstrual cycle: an in vivo study using magnetic resonance imaging (MRI). The American Fertility Society, October 1990.
15. Visoski AY, Lipshultz LI, Wun A, Grunert G, Valdes C, Dunn R, Carson SA, Cisneros P, Lamb DJ. Intracytoplasmic insertion of sperm (ICSI) for severe male factor infertility. Annual Meeting of the American Urologic Association, October 1994.
16. Hoekstra T, Witt M, Jaffe T, Carson S, Grunert G, Buster J, Casson P, Dunn R, Valdes C, Lamb D, Wun WS, Gvakhari M, Tucker M, Kattan M, Lipshultz L. Effect of sperm source on embryo grade and rate of cell division after intracytoplasmic sperm injection. Annual Meeting of the American Urological Association, New Orleans, LA, 1997.
17. Tripp BM, Gvakharia M, Carson SA, Buster JE, Casson P, Cisneros P, Grunert GM, Dunn R, Valdes CT, Lipshultz LI, Lamb DJ. The treatment of infertile patients with an abnormal sperm penetration assay (SPA) by intracytoplasmic sperm injection. Annual Meeting of the American Urological Association, New Orleans, LA, 1997.
18. Dunn R, Wun WS, Valdes C, Grunert G. The sperm from electroejaculation (EEJ) and MESA gives equal pregnancy outcomes compared to masturbation for ICSI in ART trials. 10th World Congress on In Vitro Fertilization, Vancouver, BC, Canada, 1997.
19. Dunn RC, Wun WS, Valdes CT, Grunert GM. Low pregnancy rates by day 2 ICSI reinsemination is due to the low quality of reinseminated preembryos. 10th World Congress on In Vitro Fertilization, Vancouver, BC, Canada, 1997.
20. Wun WS, Angus, S, Valdes C, Dunn R, Lamb D, Lipshultz L, Grunert G. Blastulation occurrence is better by the conventional insemination than the ICSI procedure. 10th World Congress on In Vitro Fertilization, Vancouver, BC, Canada, 1997.
21. Wun WS, Wunn CC, Valdes C, Dunn R, Grunert G. The percentage of blastulation (PB) correlates with patient age and pregnancy outcome. 10th World Congress on In Vitro Fertilization, Vancouver, BC, Canada, 1997.
22. Tripp BM, Lewitton M, Hoekstra T, Gvakharia M, Carson SA, Buster JE, Casson P, Cisneros P, Grunert GM, Dunn R, Valdes CT. Intracytoplasmic sperm injection results as evaluated by multiple outcome assessment is not influenced by male factors. American Society for Reproductive Medicine, Cincinnati, OH, October 1997.
23. Grunert GM, Grunert MB, Wun CC, Valdes C, Dunn R, Wun WSA. Blastulation rate of embryos from oocytes matured in vitro. American Society for Reproductive Medicine, Cincinnati, OH, October 1997.
24. Wun WSA, Valdes C, Dunn R, Wun CC, Grunert GM. The development of one pronucleus "zygotes" is abnormal. American Society for Reproductive Medicine, Cincinnati, OH, October 1997.
25. Wun WS, Dunn RC, Valdes CT, Grunert GM. Mathematical model to detect the rate limiting step of A.R.T. Pacific Coast Fertility Society Annual Meeting, Indian Wells, CA, April 1998.
26. Angus SC, Valdes CT, Dunn RC, Wun CC, Grunert GM, Wun WSA. Low blastulation rate by ICSI is not due to the injection of Polyvinyl-pyrrolidone (PVP) or the interference of the mixture of the injected spermatozoon with the ooplasm. American Society for Reproductive Medicine, San Francisco, California, October 1998.
27. Wun WSA, Angus SC, Wun CC, Chen BC, Dunn RC, Valdes CT, Grunert GM. Augmentation of embryo development by combination of optimal medium. American Society for Reproductive Medicine, San Francisco, California, October 1998.
28. Wun WSA, Valdes CT, Dunn RC, Wun CC, Grunert GM. Low blastocyst formation rate by ICSI is not due to the subnormal sperm quality. American Society for Reproductive Medicine, San Francisco, California, October 1998.
29. Grunert GM, Dunn RC, Valdes CT, Wun CC, Wun WSA. Comparison of Wallace, Frydman DT, and Cook embryo transfer catheter for IVF: A prospective randomized study. American Society for Reproductive Medicine, San Francisco, California, October 1998.
30. Strandell A, Thorburn J, Tronstad SE, Hompes P, Boer-Meisel M, Bemelman W, Peters A, Leach R, Diamond M, Valdes C, Dunn R. Effectiveness and safety of a bioabsorbable carbohydrate solution for prevention of postoperative adhesions in pelvic surgery. American Society for Reproductive Medicine, San Francisco, California, October 1998.
31. Dunn RC, Valdes CT, Grunert GM, Wun CC, Wun WSA. Zona dissolution (ZD) enhances pregnancy for ICSI patients. European Society of Human Reproduction and Embryology, Tours, France, June 1999.
32. Dunn RC, Valdes CT, Grunert GM, Wun CC, Wun WSA. ICSI gives lower pregnancy and implantation rates than IVG. European Society of Human Reproduction and Embryology, Tours, France, June 1999.
33. Dunn RC, Valdes CT, Bemelman WA, Peters AAW, Strandell AM, Thorburn JO, et al. Effectiveness and safety of a bioabsorbable adhesion control barrier solution for prevention of postoperative adhesions in a pilot clinical study. European Society of Human Reproduction and Embryology, Tours, France, June 1999.
34. Bemelman WA, Peters A, Strandell A, Thornburn J, Tronstad S, Hompes P, Boer-Meisel M, Leach R, Diamond M, Valdes C, Dunn R. Effectiveness and safety of a bioabsorbable adhesion barrier solution for the prevention of postoperative adhesions in a pilot clinical study. European Association for Endoscopic Surgery, Linz, Austria, June 1999.
35. U.S. Gonal F Multicenter Clinical Trial Group. A phase III, open-label, multicenter study to evaluate the safety and efficacy of recombinant human follicle stimulating hormone (Gonal-F) administered by the subcutaneous route during pituitary desensitization, for multiple follicle development in 100 women undergoing In-Vitro Fertilization and Embryo Transfer. European Society of Human Reproduction and Embryology, Tours, France, June 1999.
36. Wun WA, Grunert GM, Dunn RC, Valdes CT, Schenk LM, Mangal RK. The size and trophectoderm of blastocysts are sensitive indicators for pregnancy. American Society for Reproductive Medicine, Orlando, FL, October 2001.
37. Wun WSA, Grunert GM, Dunn R, Valdes C, Schenk L, Mangal R. The quality of inner cell mass (ICM) correlates with clinical spontaneous abortion (SAB). American Society for Reproductive Medicine, Seattle, WA, October 2002.
38. Grunert GM, Wun WSA, Cheung SW, Dunn RC, Valdes CT, Schenk L. Blastocyst formation is not an indication of genetically normal embryos. American Society for Reproductive Medicine Seattle, WA, October 2003.
39. Grunert GM, Dunn RC, Valdes CT, Schenk L, Mangal RK, Wun WA. Prostacyclin agonist (Iloprost) enhances human embryo development. American Society for Reproductive Medicine/Canadian Fertility and Andrology Society, Montreal, Quebec, Canada, October 2005.
40. Angus S, Grunert GM, Dunn RC, Valdes CT, Schenk LM, Mangal RK. No advantage of using the sequential GIII media versus the single media global. American Society for Reproductive Medicine, New Orleans, LA, October 2006.
41. Wun WA, Cooper ML, Grunert GM, Dunn RC, Valdes CT, Schenk L. The number of pronuclei does not reflect the number of ploidy. American Society for Reproductive Medicine, New Orleans, LA, October 2006.